Michiko Sakyô plays the Madame O of the title, a highly successful female surgeon with issues. The frowning, matronly Sakyo is all business at the clinic, but come nightfall she paints on a smile and hits all of Tokyo ’s seediest gin joints to pick up men. After a roll in the hay, Madame O reaches for her lancet, marks her male prey and presses some syphilis-moistened swabs into their wounds as they sleep. Sakyo is lashing out at men after being gang raped on a beach as a teenager. She hates all men, and hates herself just a little bit more, as she mutilates her own genitalia sans anesthetic. A fellow male doctor (Akihiko Kaminara) catches her in the act and promptly falls head over heels in love with her! – YEEEEEEEEEEEcccccccccchhhhhhhhhhhh.
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