
Maria plays herself in different time periods throughout her own life. We see the past, present and scenes from time spent getting care in Duluth. She is surrounded by odd family members and friends played by Mo Collins, Ana Gasteyer, Ed Begley, Jr., Bridget Everett, Dean Cain and more. One of the more interesting storytelling methods is having Comedians of Comedy partners Brian Posehn and Patton Oswalt break character to make sure Bamford doesn't replicate other shows led by comedians.